Deep Centered Mental Health
Call Now: (512) 956-6463 Book an appointment
Refer a Patient Patient Portal

SPRAVATO® (esketamine): An Advanced Treatment For Depression

An FDA-approved treatment for depression when medication isn’t enough.

Call (512) 956-6463Book an Appointment

SPRAVATO® (esketamine) is an FDA-approved nasal spray used to treat adults with treatment-resistant depression and depressive symptoms associated with major depressive disorder. Unlike traditional antidepressants, which mainly affect serotonin, SPRAVATO® works on a different brain pathway involved in mood and emotional processing.

Treatment takes place in our supervised clinical setting and is intended for individuals who have not experienced meaningful improvement with standard antidepressant medications. Many patients begin to notice improvements in symptoms within days to weeks.

How SPRAVATO® Works

Depression can affect how the brain regulates mood, stress, and emotional processing over time. In some individuals, the brain pathways involved in these functions may not respond adequately to traditional antidepressant medications alone.

SPRAVATO® works by acting on a different system in the brain involved in communication between nerve cells. By targeting this pathway, SPRAVATO® may help improve how the brain regulates mood and emotional responses.

SPRAVATO® is administered as a nasal spray in our supervised and relaxing clinical setting. Patients are monitored to ensure safety and comfort during treatment.

Watch the video below to learn more about how SPRAVATO® works for individuals with treatment-resistant depression.

When Depression Hasn’t Improved With Medications Alone, Spravato Can Help

verified
FDA-Approved
science
Evidence-Based Treatment Beyond Antidepressants
local_hospital
Outpatient, Clinic-Based Monitored Care
trending_up
70% Response Rate
check_circle
53% Remission Rate
SPRAVATO® is an FDA-approved prescription nasal spray

Depression doesn’t always respond to traditional antidepressant medications. When symptoms persist after trying two or more antidepressants, this is commonly referred to as treatment-resistant depression. This experience is more common than many people realize and can leave individuals feeling hopeless after trying multiple medications without success.

SPRAVATO® is an FDA-approved nasal spray for adults whose depression has not improved with medication alone.

Clinical studies have shown that SPRAVATO® can lead to meaningful symptom improvement for many patients. In these studies, a higher proportion of patients achieved remission compared to antidepressant treatment alone.

A Professional Perspective

Edgar Hernandez, MD

Chief Medical Officer

To everyone facing the challenges of depression, know that hope can take many forms. At Deep Centered Mental Health, we are committed to offering compassionate, evidence-based care through a holistic and individualized approach.

SPRAVATO® (esketamine) therapy provides a rapidly acting option for individuals living with depression who have not experienced adequate relief with traditional medications or psychotherapy alone. For patients feeling stuck, overwhelmed, or worn down by persistent symptoms, Esketamine may offer a renewed sense of possibility and meaningful improvement.

You are not alone on this journey as support, hope, and new options are available.

Every step you take reflects your strength, and brighter days remain within reach. Let us walk alongside you on your path toward healing.

SPRAVATO® + Antidepressant

70%
Response at 4 Weeks
53%
Remission at 4 Weeks

Antidepressant Alone

50%
Response at 4 Weeks
30%
Remission at 4 Weeks

Why SPRAVATO® Is Effective When Medications Alone Haven’t Been Enough

Some people continue to experience significant depressive symptoms even after trying multiple antidepressant medications. When depression doesn’t improve after two or more medication trials, it’s often referred to as treatment-resistant depression.

In these cases, continuing to adjust medications alone may not lead to meaningful symptom relief. SPRAVATO® offers an evidence-based approach for individuals who haven’t responded to standard antidepressant treatment.

Why Trying Another Medication May Not Help

Antidepressant medications can be effective for many people. However, for those struggling with treatment-resistant depression, repeatedly switching or adding medications often leads to diminishing returns rather than sustained improvement.

This experience is more common than many people think. It can feel frustrating and discouraging, especially for individuals who have tried different medications for months or years without feeling noticeably better.

What This Means

If you have already tried two or more medications without sufficient improvement in symptoms, the likelihood of another medication alone being effective may decrease. This is one of the reasons SPRAVATO® is a powerful alternative for people with treatment-resistant depression.

SPRAVATO® is FDA-approved and has demonstrated symptom improvement in clinical studies involving patients who had not responded to traditional antidepressant approaches.

Is SPRAVATO® (esketamine) An Option For You?

Have you tried two or more antidepressants without feeling noticeably better?

Have medication changes or side effects made it difficult to stay on your prescriptions?

Are symptoms still interfering with your ability to function day to day?

If you answered “Yes” to any of these questions, Spravato may be an option for you.

You’re not alone and there is hope. SPRAVATO® is an FDA-approved advanced treatment for people struggling with treatment-resistant depression. Schedule a free consultation today to see if Spravato is a good option for you.

Why Choose Deep Centered Mental Health For Your SPRAVATO® Treatment

Backed by Science

Backed by Science

SPRAVATO® is FDA-approved for adults with treatment-resistant depression and has been studied in large, controlled clinical trials. At Deep Centered Mental Health, we integrate this evidence-based treatment into a personalized care plan tailored to your needs.

Powerful Clinical Results

Powerful Clinical Results

Clinical studies show that 53% of patients receiving SPRAVATO® alongside an oral antidepressant achieved remission within four weeks, compared to 31% with antidepressant treatment alone. Continued treatment has also been shown to reduce the risk of relapse.

Covered By Insurance

Covered By Insurance

Many major insurance plans cover SPRAVATO® for treatment-resistant depression. Our team assists with insurance verification, benefits review, and authorization so you can focus on your care.

Care With Medical Oversight

Care With Medical Oversight

SPRAVATO® is administered in our relaxing clinic under medical supervision, with monitoring before and after each session to ensure your safety and comfort.

Designed to Fit Your Life

Designed to Fit Your Life

Treatment sessions are scheduled in advance and include a monitored observation period. Care is delivered in our comfortable clinics where you can relax and focus on feeling better.

Compassionate, Integrated Care

Compassionate, Integrated Care

Our psychiatric providers and care team guide you through the entire SPRAVATO® process, coordinating treatment alongside therapy and medication management so you feel supported from evaluation through ongoing care.

Journeys to Healing

Real experiences shared by patients who turned therapy into transformation.

“

It started with a smile and I was greeted with warming energy. Tralynza created a safe place and easy going atmosphere to communicate. Kudos to this veteran for continuing to make a difference in our communities.

“

Omg, I had the BEST experience of my life from the moment I parked my vehicle, to being greeted til finished. My Soul feels renewed as well I think there’s a light of awakening. Thanks, Deep Centered.

“

My therapist is amazing. They are fast and easy to get started with. Would recommend 1000% My child has been using them since 2020 and I recommend to everyone looking for a therapist.

Understand The Process

See answers to FAQs people have about Spravato.

Who is SPRAVATO® for?

SPRAVATO® is most often used for adults with depression who have not found sufficient relief from antidepressant medication alone. It is prescribed for people with treatment-resistant depression and is used alongside an oral antidepressant as part of a broader care plan.

Is SPRAVATO® safe?

SPRAVATO® is FDA-approved and administered in a clinical setting under medical supervision. Treatment follows established safety protocols, including monitoring before and after each session

How long does SPRAVATO® treatment take?

Each SPRAVATO® visit includes time for administration and monitoring. Patients remain in the clinic for at least two hours per session. Treatment schedules vary but often begin with more frequent visits before transitioning to maintenance sessions.

Does SPRAVATO® have side effects?

Some people experience temporary side effects such as changes in perception, dizziness, or nausea following treatment. These effects typically resolve the same day. Your provider will review potential side effects and answer questions before treatment begins.

Is SPRAVATO® covered by insurance?

Many major insurance plans cover SPRAVATO® for treatment-resistant depression. Our team assists with insurance verification, prior authorization, and coordination of benefits so you are informed before starting care.

calendar_clock
Book an Appointment
call